Quercetin

Характеристики

INCI: Quercetin
CAS: 117-39-5
EC: 204-187-1
IUPAC: 4H-1-Benzopyran-4-One, 2-(3,4-Dihydroxyphenyl)-3,5,7-Trihydroxy-
Функции: антиоксидант, кондиционирование кожи

Описание

Quercetin is a polyphenol flavonoid found in lots of plants, such as red onions, broccoli, and blueberries. The reason it is in cosmetics is that - similar to other polyphenols - it is a strong antioxidantand has anti-inflammatory properties.

Other than that, a study also showed that adding quercetin to sunscreens helped to stabilize the otherwise not very stable chemical UV filters avobenzone and octinoxate against degradation -- and it did better than traditional stabilizers like octocrylene and vitamin E!

There are also some studies into the use of quercetin as a skin whitening agent, but after some conflicting results, the conclusion is that "quercetin is not effective in cosmetic applications as a whitening ingredient". It also shows minor cytotoxicity when compared to some of its polyphenol derivatives (such as rutin), so quercetin is a good example where more is not better.

Доказательная база и научные исследования

1

Bonina, Francesco, Maria Lanza, Lucia Montenegro, Claudio Puglisi, Antonio Tomaino, Domenico Trombetta, Francesco Castelli, and Antonella Saija. 1996. “Flavonoids as Potential Protective Agents against Photo-Oxidative Skin Damage.” International Journal o
2

Boots, Agnes W., Lonneke C. Wilms, Els L. R. Swennen, Jos C. S. Kleinjans, Aalt Bast, and Guido R. M. M. Haenen. 2008. “In Vitro and Ex Vivo Anti-Inflammatory Activity of Quercetin in Healthy Volunteers.” Nutrition 24 (7): 703–10.
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3

Choi, Moon-Hee, and Hyun-Jae Shin. 2016. “Anti-Melanogenesis Effect of Quercetin.” Cosmetics 3 (2): 18.
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4

Kitagawa, Shuji, Yuko Tanaka, Manami Tanaka, Kanako Endo, and Akiko Yoshii. 2009. “Enhanced Skin Delivery of Quercetin by Microemulsion.” Journal of Pharmacy and Pharmacology 61 (7): 855–60.
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5

Scalia, Santo, and Matteo Mezzena. 2010. “Photostabilization Effect of Quercetin on the UV Filter Combination, Butyl Methoxydibenzoylmethane–Octyl Methoxycinnamate.” Photochemistry and Photobiology 86 (2): 273–78.
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