S-Mu-Conotoxin Cniiic (XEP-018)

Характеристики

INCI: S-Mu-Conotoxin Cniiic
Рус.: XEP-018
CAS: 936616-33-0
IUPAC: L-Cysteinamide, 5-Oxo-L-Prolylglycyl-L-Cysteinyl-L-Cysteinyl-L-Asparaginylglycyl-L-Prolyl-L-Lysylglycyl-L-Cysteinyl-L-Seryl-L-Seryl-L-Lysyl-L-Tryptophyl-L-Cysteinyl-L-Arginyl-L-.Alpha.-Aspartyl-L-Histidyl-L-Alanyl-L-Arginyl-L-Cysteinyl-, Cyclic (3.Fwdarw.
Функции: защита кожи

s-mu-conotoxin cniiic - одноцепочечный белк улитки, синтетически продуцируемый, чтобы быть идентичным mu-conotoxin cniiic, который содержится в конусе. Белок содержит 22 аминокислоты и состоит из правильной последовательности 20 стандартных аминокислот.

Описание

Though its name does not reveal it, Mu-Conotoxin Cniiic is a 22 amino acid peptide molecule that belongs to the "Botox-in-a-jar" type of topical muscle relaxers. (If you are new to these types of molecules, we wrote more about it at Argireline.)

It is a biomimetic peptide, meaning that it tries to copy the behavior of the natural peptide found in the venomous marine cone snail called Conus consors. Biologically speaking, the molecule acts as a modulator of the neuromuscular transmission that translates to being an instant line relaxer when it comes to cosmetics. According to the manufacturers in-vivo (made on people) study, a single application with 3% XEP-018 on 33 people results in a visible and significant reduction of wrinkle depth and rugosity 2 hours after application. Sounds pretty good.

Исследования и доказательная база: S-Mu-Conotoxin Cniiic

1

Favreau, Philippe, et al. "A novel µ‐conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1. 2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors." British journal of pharmacology 166.5 (2012): 1654-1668.
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