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Neutral
buffering masking

Tromethamine

Characteristics

INCI
Tromethamine
CAS
77-86-1
EC
201-064-4
IUPAC
1,3-Propanediol, 2-Amino-2-(Hydroxymethyl)-
Functions
buffering, masking
EU Restr.
III/61

Description

Tromethamine is a pH adjuster and buffering ingredient used in many skincare and haircare formulas. In simple terms, it helps keep a product at the right acidity level so the formula stays stable, comfortable, and effective. It’s an alkaline ingredient, so it can neutralize overly acidic components and help balance formulas that might otherwise feel too harsh or behave unpredictably.

For skin and hair, tromethamine doesn’t act like an active treatment on its own, but it plays an important behind-the-scenes role. By helping maintain the ideal pH, it can support the performance of ingredients such as exfoliating acids, preservatives, and certain gels or emulsions. This matters for people using acid-based products, lightweight serums, cleansers, or styling products, where formula stability and texture are especially important.

Who benefits? Basically anyone using well-formulated products can benefit from it, since it helps the product work as intended. The main caveat is that, like any ingredient, it depends on the overall formula: tromethamine itself is not the star ingredient, and its effect is mostly indirect. If you’re sensitive to very alkaline products, the finished formula’s pH matters more than the ingredient name alone.

Found in products (7 414 total)

Hair
Face Care
Synonyms
— Tromethamine "Tromethamine" (Hydroxymethyl) Trisaminomethane *Tromethamine Tham Tris(Hydroxymethyl)aminomethane Trisaminomethane Trometamol Tromethamine - (0.3%) Tromethamine - (0.30%) Tromethamine () Tromethamine (*) Tromethamine (0.04%) Tromethamine (0.3%) Tromethamine (0.32%)