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Neutral
skin conditioning skin protecting

SH-Oligopeptide-2

Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2

Characteristics

INCI
SH-Oligopeptide-2
Ru.
Insulin-like growth factor 1, IGF-1, rh-Oligopeptide-2
Functions
skin conditioning, skin protecting
it is a single chain recombinant human peptide,produced by fermentation in e. coli. the starting gene is a synthesized copy of the human gene which codes for insulin-like growth factor used as such or adapted to the production host.

Description

Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1. This guy consists of 70 amino acids and, similar to EGF, it is also claimed to stimulate cell proliferation and wound healing. There is also a study that indicates EGF and IGF1 work in synergy to promote keratinocyte (skin cell) proliferation. 

The topic of Growth Factors in skincare is complex and controversial. If you are new to it, read our shiny explanation on EGF to get a (hopefully) balanced impression about the pros and cons.

Evidence & research

Scientific publications & sources 1
  • 1
    Krane, Jeffrey F., et al. "Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor." Journal of investigative de

Found in products (444 total)

Hair
Face Care
Synonyms
(SH-Oligopeptide-2 [SH-Oligopeptide-2 IGF-1 IGF-1 (SH-Oligopeptide-2) IGF-1 (SH-Oliogopeptide-2) Insulin-like growth factor 1 rh-Oligopeptide-2 rh-Oligopeptide-2 (Igf) rh-Oligopeptide-2(Igf) SH- Oligopeptide-2 Sh-Oligopeptide-2 SH-Oligopeptide-2 (0.0001 Ppm) SH-Oligopeptide-2 (0.03Ppb) SH-Oligopeptide-2 (0.1Ppb) SH-Oligopeptide-2 (8Ppb)