Palmitoyl Pentapeptide-4
Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3
Characteristics
- INCI
- Palmitoyl Pentapeptide-4
- Ru.
- Matrixyl, Pal-KTTKS, Formerly Palmitoyl Pentapeptide-3
- Functions
- skin conditioning
Для кого подходит
Description
A pretty famous and better-researchedpeptide consisting of five amino acids (the building blocks of all proteins). It was created in a joint effort by the French ingredient supplier, Sederma and the cosmetics industry big shot, Procter&Gamble.
The amino acid sequence of the peptide is lysine–threonine–threonine–lysine–serine (KTTKS). Sometimes, it's also called collagen pentapeptide, as it's a subfragment of skin-structure-giving type I collagen. The KTTKS amino sequence is then attached for better oil solubility and skin penetration to palmitic acid and BOOM; we get Palmitoyl Pentapeptide-4.
Though most research is manufacturer sponsored, the clinical studies about Palmitoyl Pentapeptide-4 are promising. In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%).
There are also studies comparing Palmitoyl Pentapeptide-4 with anti-aging gold standard, retinol. One of them compared 3ppm Pal-KTTKS with 700 ppm (0.07%) retinol and found that they showed similar wrinkle improving ability with the peptide showing better skin tolerability.
Bottom line, if you are into peptides, this is a good one to try.
Evidence & research
-
1
International Journal of Cosmetic Science, Dec 1, 2011, Topically applied KTTKS: a review
Found in products (2 064 total)
Наиболее часто встречается в продукции Olay (115 продуктов)
